Hi Newbride,
Wow.. you had a large follicles. Hope this article help you:
Ovarian Hyper Stimulation Syndrome (OHSS)
OHSS occurs when the ovary overreacts to superovulation drugs. While the exact cause of OHSS is not known, and doctors can not predict who will suffer from it, women with PCOS are more susceptible to it because they have a large number of semi-ripe follicles in their ovaries already. These semi-ripe follicles will all respond to superovulation, resulting in an unusually large number of follicles at egg pickup. The down side of having such a large number of follicles is that they are usually of a poor quality, with only a few being suitable for fertilisation.
When IVF is undertaken, 10% to 20% of patients will experience mild OHSS. Symptoms might include nausea, sore swollen stomach, and some dehydration. It is uncomfortable, but dissipates within a few days after egg pickup. One percent of women will experience severe OHSS requiring hospitalisation and stomach draining. Women with PCOS have a significantly higher risk of severe OHSS than the general populus.
The complications caused by the condition can be life-threatening, particularly difficulties with breathing and blood clotting. Human Chorionic Gonadotropin (HCG) and other hormones leak from the ovaries into the pelvis and stomach cavity, in response to superovulation. These areas become full of fluid and the presence of the hormones also draws fluid from the blood circulatory system leaving the blood more concentrated and prone to clotting. These fluids quickly fill the lungs and any other body space available, making breathing extremely difficult. Patients can gain 10 – 12 kilos of fluid in a few days as a result of OHSS.
Blood clotting is a very serious complication caused by the release of hormones into the body. Patients are routinely placed on aspirin therapy following IVF egg pick-up, however in severe cases injections of heparin or other anti-clotting agents are required.
The presence of these hormones in the digestive tract creates extreme nausea. Patients are often very dehydrated because even drinking water becomes difficult. This sense of dehydration is exacerbated by the massive fluid imbalance in the body. They are unable to eat or digest food.
Some things can be done to prevent OHSS.
* Eat a high protein diet throughout the IVF treatment, especially during the few weeks after egg pickup. Patients in hospital are treated with protein drips in an effort to neutralise the effect of the leaking hormones on the body, however patients at home could try drinking Sustagen for a similar effect.
* Drink three litres of water a day to help prevent dehydration.
* ENSURE that your IVF Specialist closely monitors you while on FSH treatments. Even if you are concerned about looking disrespectful or rude, insist that your doctor closely monitor the growth of follicles via ultrasound during FSH treatment. As a patient diagnosed with PCOS, they should be checking you every few days to help avoid OHSS. It might mean abandoning treatment mid-cycle, but that is preferable to hospitalisation and the risks of OHSS.
For more information, there is a good fact sheet on OHSS at:
http://www.child.org.uk/html/malta.php/factsheets/60/