IVF/ICSI Support Group

WhenItComes

New Member
I respond poorly to IVF stimulation despite normal AMH and hormonal profiles. And I guess egg quality has deteriorated over last 3 years - I am 36 years old now. I got only 1 c grade day 5 blast after first round..decided to do one more round to bank embryos - this time it was only 1 b grade day 6 blast. So waiting for doc to decide if I need to endo scratch or just transfer embryos straight. How about you - how many embryos do you have?

I just did the egg retrieval 2 days ago.. 10 eggs but all found abno
All got fertilised but they r fragmented and at this pt in time, no one is good for trf, even at D2.

It is devastating.
Hmmm. I just done my ER this wednesday. Out of 10, 9 abnormal and 1 underwent icsi. However, it did not split at D2, which is today. Dr advise to keep it until day 5 because he can see the disappointment from me and my husband. At my age of 32 it is unexpected. Overall my egg quality very poor. Dr even suggest me to do further ivf at KK or any subsidised hospital. Maybe some sister help can give advise on how could i improve my egg quality?? I cried hours.. non stop.. like no help..
 


JOJO_POS

Member
I just did the egg retrieval 2 days ago.. 10 eggs but all found abno


Hmmm. I just done my ER this wednesday. Out of 10, 9 abnormal and 1 underwent icsi. However, it did not split at D2, which is today. Dr advise to keep it until day 5 because he can see the disappointment from me and my husband. At my age of 32 it is unexpected. Overall my egg quality very poor. Dr even suggest me to do further ivf at KK or any subsidised hospital. Maybe some sister help can give advise on how could i improve my egg quality?? I cried hours.. non stop.. like no help..
May I know what type of injection u took? My first cycle also poor egg quality and Dr added in additional growth hormone injection for better quality. Going for ER on Monday, will see if there is any improvement.
 
Hmmm. I just done my ER this wednesday. Out of 10, 9 abnormal and 1 underwent icsi. However, it did not split at D2, which is today. Dr advise to keep it until day 5 because he can see the disappointment from me and my husband. At my age of 32 it is unexpected. Overall my egg quality very poor. Dr even suggest me to do further ivf at KK or any subsidised hospital. Maybe some sister help can give advise on how could i improve my egg quality?? I cried hours.. non stop.. like no help..
Which hospital are you in? How do they know 9 are abnormal even before attempting ICSI? I thought will only differentiate between mature and immature eggs?

There’s still hope! Your embryo may be a late bloomer. And you have 100% fertilisation rate; that is a blessing in itself that many tend to overlook. At least you only need to work on one aspect moving forward, rather than worry about both embryo and sperm quality. Usually for quality (regardless of egg or sperm), local doctors will advise taking Vit C, Vit E and Co-enzyme/Ubiquinol as a starting point.
 

connie_hopeful

Well-Known Member
I just did the egg retrieval 2 days ago.. 10 eggs but all found abno


Hmmm. I just done my ER this wednesday. Out of 10, 9 abnormal and 1 underwent icsi. However, it did not split at D2, which is today. Dr advise to keep it until day 5 because he can see the disappointment from me and my husband. At my age of 32 it is unexpected. Overall my egg quality very poor. Dr even suggest me to do further ivf at KK or any subsidised hospital. Maybe some sister help can give advise on how could i improve my egg quality?? I cried hours.. non stop.. like no help..
You can check with doctor if dhea will it help you or not to improve quality in your case. Do check with doctor as dhea cannot anyhow eat.
 
You can check with doctor if dhea will it help you or not to improve quality in your case. Do check with doctor as dhea cannot anyhow eat.
Connie is right. You often read others like DHEA and myo-inositol being helpful for egg quality but need to be careful with these 2. Not everybody can take and specific to one’s body and after bloodwork confirmation... that’s probably why these 2 are not readily available off the shelf here.

For example, DHEA can increase androgens while myo-inositol decreases insulin and androgens. So ladies with high testosterone (a type of androgen) to begin with should not be be taking DHEA, and those with low testosterone may not be compatible with myo-inositol (cause you need the correct balance of hormones).
 
I just did the egg retrieval 2 days ago.. 10 eggs but all found abno


Hmmm. I just done my ER this wednesday. Out of 10, 9 abnormal and 1 underwent icsi. However, it did not split at D2, which is today. Dr advise to keep it until day 5 because he can see the disappointment from me and my husband. At my age of 32 it is unexpected. Overall my egg quality very poor. Dr even suggest me to do further ivf at KK or any subsidised hospital. Maybe some sister help can give advise on how could i improve my egg quality?? I cried hours.. non stop.. like no help..
I have been taking multi vit for abt 3 mths. But I took ubiquinol only after knowing no embryos to transfer due to poor egg quality. Doc did not discourage taking but told me there is no studies that it helps improve egg quality. I'm taking it for 1 mth already. Not sure will improve anot but take better than not taking. Hope my next fresh cycle has better eggs.
 

risther

Member
I just did the egg retrieval 2 days ago.. 10 eggs but all found abno


Hmmm. I just done my ER this wednesday. Out of 10, 9 abnormal and 1 underwent icsi. However, it did not split at D2, which is today. Dr advise to keep it until day 5 because he can see the disappointment from me and my husband. At my age of 32 it is unexpected. Overall my egg quality very poor. Dr even suggest me to do further ivf at KK or any subsidised hospital. Maybe some sister help can give advise on how could i improve my egg quality?? I cried hours.. non stop.. like no help..
Did you increase your intake of protein especially during stimulations? Supplements like ubiquinol can improve egg quality to prepare for next cycle as per my knowledge. As long as your AMH is ok I’m sure your egg quality can be improved.
 
Hi Sisters! Seek your advise ? Just see the doctor check blood test report shown that my blood glucose tolerance is poor got a bit diabetic ask me to see their specialist doctor in KK before proceed to IVF. Feel so upset in my heart why Bec got slight diabetic I cannot start IVF! Doctor said until my blood sugar is back to normal then can proceed IVF ! .
 

bbcola

Member
Hi Sisters! Seek your advise ? Just see the doctor check blood test report shown that my blood glucose tolerance is poor got a bit diabetic ask me to see their specialist doctor in KK before proceed to IVF. Feel so upset in my heart why Bec got slight diabetic I cannot start IVF! Doctor said until my blood sugar is back to normal then can proceed IVF ! .
I was in a similar situation back then, not allowed to start IVF due to slight thyroid issue. But do trust your doc that it's for your good, because complications can be really serious if you develop gestational diabetes. Our ultimate goal is a live birth and not just a positive pregnancy test right? Jiayou!
 
Hi ! Tks for advise ! To check and see the diabetic doctor to monitor the blood sugar level first . Should I go Polyclinic to see the doctor or to see the specialist doctor in KK which the doctor recommend . Which one should I see ? I am lost suddenly the doctor said my blood sugar tolerance is poor got slight diabetic Bec I seldom drink sweet drink . Feel so sad can’t start my IVF . Don’t know drag until when .
 

WhenItComes

New Member
May I know what type of injection u took? My first cycle also poor egg quality and Dr added in additional growth hormone injection for better quality. Going for ER on Monday, will see if there is any improvement.
I was on puregon & menopur for 14 days. Egg growth a bit slow .. day 5 only 6 eggs seen; day 10 finally saw 10 eggs but size were small at 15mm. So dr prescribed another 4 days of injection (menopur) until trigger at 14th day.
 

WhenItComes

New Member
Which hospital are you in? How do they know 9 are abnormal even before attempting ICSI? I thought will only differentiate between mature and immature eggs?

There’s still hope! Your embryo may be a late bloomer. And you have 100% fertilisation rate; that is a blessing in itself that many tend to overlook. At least you only need to work on one aspect moving forward, rather than worry about both embryo and sperm quality. Usually for quality (regardless of egg or sperm), local doctors will advise taking Vit C, Vit E and Co-enzyme/Ubiquinol as a starting point.
Thanks for being postive with my condition. It cheers me up!! I am now with dr.tan. He also advise me not to give up & continue with all possible way to help like tcm, acupunture, taking supplements.. i think he dont want me to lose my hope.

Basically they will do polar body to differentiate mature, immature and abnormal egg after retrieval. He showed me the lab note...... so end up tbey injected sperm into 1 looks normal egg ( but it is fragmented as well)...
 

WhenItComes

New Member
Did you increase your intake of protein especially during stimulations? Supplements like ubiquinol can improve egg quality to prepare for next cycle as per my knowledge. As long as your AMH is ok I’m sure your egg quality can be improved.
My amh about 10.. it is at borderline according to Dr. So, i could not waste my time.. i bought ubiquinol & rosytime, will consume them together with folic acid & vitamin D.. hope it helps..
 

WhenItComes

New Member
My amh about 10.. it is at borderline according to Dr. So, i could not waste my time.. i bought ubiquinol & rosytime, will consume them together with folic acid & vitamin D.. hope it helps..
Forgot to say.. i ate eggs nearly everyday during stimulation and meat since i try to conceive 2 years ago.
 

WhenItComes

New Member
I have been taking multi vit for abt 3 mths. But I took ubiquinol only after knowing no embryos to transfer due to poor egg quality. Doc did not discourage taking but told me there is no studies that it helps improve egg quality. I'm taking it for 1 mth already. Not sure will improve anot but take better than not taking. Hope my next fresh cycle has better eggs.
Same to me. I started it today.. going to take whatever i can and start exercise more. Hope next cycle will have better egg quality.. plan for next cycle in 3 months time
 

WhenItComes

New Member
May I know what type of injection u took? My first cycle also poor egg quality and Dr added in additional growth hormone injection for better quality. Going for ER on Monday, will see if there is any improvement.
Pls posted the update after ER. I really hope hormon dosage will help our problem..
 
I was on puregon & menopur for 14 days. Egg growth a bit slow .. day 5 only 6 eggs seen; day 10 finally saw 10 eggs but size were small at 15mm. So dr prescribed another 4 days of injection (menopur) until trigger at 14th day.

Actually to reach 15mm at stimm day 10 is honestly not bad. All growing uniformly (albeit slowly) is still better than having 1-3 leading follicles growing way ahead of others... just mean extending stimm period, rather than at a crossroad to choose whether to ‘sacrifice’ them. Think the focus now is to work on quality. 加油! May want to change to gonal f for your next IVF. I don’t have good experience with puregon /menopur. Used them for SO-IUIs separately.
 

Dreamscometrue

Well-Known Member
Hi Sisters! Seek your advise ? Just see the doctor check blood test report shown that my blood glucose tolerance is poor got a bit diabetic ask me to see their specialist doctor in KK before proceed to IVF. Feel so upset in my heart why Bec got slight diabetic I cannot start IVF! Doctor said until my blood sugar is back to normal then can proceed IVF ! .
Because if diabetic, risk of miscarriage is increased, according to a doc I see in nuh. But blood glucose test is not routinely done b4 IVF though.. just wondering how come ur doc asked u to do
 

WhenItComes

New Member
Actually to reach 15mm at stimm day 10 is honestly not bad. All growing uniformly (albeit slowly) is still better than having 1-3 leading follicles growing way ahead of others... just mean extending stimm period, rather than at a crossroad to choose whether to ‘sacrifice’ them. Think the focus now is to work on quality. 加油! May want to change to gonal f for your next IVF. I don’t have good experience with puregon /menopur. Used them for SO-IUIs separately.
My tcm practitioner also advise me to try on gonalF since i was prescribed puregon for 2xSO-IUI ( failed) and the 1st IVF cycle. Do you know whether KK will prescribed gonalF for patient? Because my dr onky give puregon..
 
Hi To all Sisters! My heart really feel very upset especially when the doctor tell you got Low ovarian reserve the high chances only can use donor eggs ! She said even I try IVF percentage is not so high ! Singapore where got donor eggs! Of course I wish can use my own egg is the best ! Deep in my heart praying to God blessing me a baby ! Let me have a chance to be a mother ! Whenever I think of baby , every night I sleep my tears will keep on flowing! Meet a lot obstacle just want to have baby! Praying God just gave me one baby I am contented!
 

Dreamscometrue

Well-Known Member
Hi To all Sisters! My heart really feel very upset especially when the doctor tell you got Low ovarian reserve the high chances only can use donor eggs ! She said even I try IVF percentage is not so high ! Singapore where got donor eggs! Of course I wish can use my own egg is the best ! Deep in my heart praying to God blessing me a baby ! Let me have a chance to be a mother ! Whenever I think of baby , every night I sleep my tears will keep on flowing! Meet a lot obstacle just want to have baby! Praying God just gave me one baby I am contented!
Hi how old are u and how long have u tried? I also have low ovarian reserve for my age.
 
Hi To all Sisters! My heart really feel very upset especially when the doctor tell you got Low ovarian reserve the high chances only can use donor eggs ! She said even I try IVF percentage is not so high ! Singapore where got donor eggs! Of course I wish can use my own egg is the best ! Deep in my heart praying to God blessing me a baby ! Let me have a chance to be a mother ! Whenever I think of baby , every night I sleep my tears will keep on flowing! Meet a lot obstacle just want to have baby! Praying God just gave me one baby I am contented!
Did you do any laparoscopy? Did your amh level decrease because of any operation?
 

Zcshop

Member
None transfer for my 1st fresh cycle. 2 embryo reach blastocycsts at D7 but unable to grade. So nothing to transfer. Waiting for my 2nd fresh next month.
Is there any special reason y they want to culture till D7? Cause D5 is already gd for trf.

U wld b doing yr 2nd fresh so soon? I will be resting for another 3-4mths before trying. The jabs r really terror to my body. In the meantime, i will take dhea, coq10 etc. Anyone tried revosit?
 

Zcshop

Member
I just did the egg retrieval 2 days ago.. 10 eggs but all found abno


Hmmm. I just done my ER this wednesday. Out of 10, 9 abnormal and 1 underwent icsi. However, it did not split at D2, which is today. Dr advise to keep it until day 5 because he can see the disappointment from me and my husband. At my age of 32 it is unexpected. Overall my egg quality very poor. Dr even suggest me to do further ivf at KK or any subsidised hospital. Maybe some sister help can give advise on how could i improve my egg quality?? I cried hours.. non stop.. like no help..
Hi, I was in the same situation as u. 1 egg was graded scored of 1 (out of 5), they just monitor until D5 to see if it improves. It didnt, so we didnt proceed with the trf. No pt incurring the egg trf cost, and spend 2ww for nothing for my case.

Is this yr 1st cycle, which clinic r u with? I was super sad for my first cycle and much calmer, although still sad, for my 2nd which i didnt get any ET at all.
 

Zcshop

Member
May I know what type of injection u took? My first cycle also poor egg quality and Dr added in additional growth hormone injection for better quality. Going for ER on Monday, will see if there is any improvement.
What was the additional jab? For me, i took gonalf for 1st cycle, 6 eggs out of 6 follicles retrieved (i hv low amh). 2 out of 6 eggs fertilised but only 1 made it to early blast for et.

2nd cycle, i did long protocol with gonalf n menupur, 4 eggs out of 8 follicled retrieved (i dunno y so many empty follicles). 4 fertilised but none made it to et. Seems like menupur doesnt suit me.
 

JOJO_POS

Member
Hi ladies! I just did ER and managed to have 18 eggs compared to my first cycle of 12. Doctor recommended to do FET due to high level of hcg and progesterone levels in my body. Can I check if anyone has delayed ET with the same reason? Also how to prepare for FET?
 
Is there any special reason y they want to culture till D7? Cause D5 is already gd for trf.

U wld b doing yr 2nd fresh so soon? I will be resting for another 3-4mths before trying. The jabs r really terror to my body. In the meantime, i will take dhea, coq10 etc. Anyone tried revosit?
The embryo were growing slow. So at D5, they have not reach blastocyst. So doc said wait for 2 more days. Then at D7, blastocysts not good for transfer.
Yes, no time to waste as i'm already 39 this yr. Every cycle is a chance. I'm betting the chance on ivf instead of natural conceive as my egg quality is poor. I'm ok with the jabs. The pain is tolerable for me. So far no side effects for my 1st cycle. Hope the 2nd will go well too.
 
Did you do any laparoscopy? Did your amh level decrease because of any operation?
No! My both Fallopian tube is blocked ! Doctor said can just remove polyps will do before I do IVF ! Feel that I might not got a chance to have a baby Bec got Low egg Overian ! Doctor suggest it best get egg donor but in Singapore where to get donor ! It was impossible ! My dreams to have a baby it seem impossible ! Feel sad and devastated !
 
No! My both Fallopian tube is blocked ! Doctor said can just remove polyps will do before I do IVF ! Feel that I might not got a chance to have a baby Bec got Low egg Overian ! Doctor suggest it best get egg donor but in Singapore where to get donor ! It was impossible ! My dreams to have a baby it seem impossible ! Feel sad and devastated !
Be positive! Blocked tubes can conceive baby too. Have to keep trying:)
 

WhenItComes

New Member
Hi, I was in the same situation as u. 1 egg was graded scored of 1 (out of 5), they just monitor until D5 to see if it improves. It didnt, so we didnt proceed with the trf. No pt incurring the egg trf cost, and spend 2ww for nothing for my case.

Is this yr 1st cycle, which clinic r u with? I was super sad for my first cycle and much calmer, although still sad, for my 2nd which i didnt get any ET at all.
Yea, this is my first. My only fertilised egg didnt make it to split. That is to said. Out of 10, i have no embroy. But i wont give up. I think my amh is acceptable eventhough it is low. The problem is quality. Plan to change to Tan Siew Buoy TCM. Anyone got any experience in TCM Tan siewbuoy?
 

WhenItComes

New Member
What was the additional jab? For me, i took gonalf for 1st cycle, 6 eggs out of 6 follicles retrieved (i hv low amh). 2 out of 6 eggs fertilised but only 1 made it to early blast for et.

2nd cycle, i did long protocol with gonalf n menupur, 4 eggs out of 8 follicled retrieved (i dunno y so many empty follicles). 4 fertilised but none made it to et. Seems like menupur doesnt suit me.
Your long protocol means injection longer than 10 days?? Mine was 14 days injection because dr said my egg grow slow.. but my tcm practitioner told me normally they only suggest to inkect for 9-11 days.
 

WhenItComes

New Member
Hi ladies! I just did ER and managed to have 18 eggs compared to my first cycle of 12. Doctor recommended to do FET due to high level of hcg and progesterone levels in my body. Can I check if anyone has delayed ET with the same reason? Also how to prepare for FET?
May i ask whether dosage increase bringing better quantity & quality of eggs?..... dr will suggest FET if you have lots of egg since injected hormon will affect implantation.
 

Uptheair

Member
Yea, this is my first. My only fertilised egg didnt make it to split. That is to said. Out of 10, i have no embroy. But i wont give up. I think my amh is acceptable eventhough it is low. The problem is quality. Plan to change to Tan Siew Buoy TCM. Anyone got any experience in TCM Tan siewbuoy?
I personally find her overrated - long queues, attitude issues and don’t really work for me. There are other better TCM physicians out there. Then again, it is a personal opinion and experience from seeing her some years ago.
 

JOJO_POS

Member
May i ask whether dosage increase bringing better quantity & quality of eggs?..... dr will suggest FET if you have lots of egg since injected hormon will affect implantation.
Oh I see. My previous cycle I only have 4 eggs to freeze and this round I have 7. Dr did say the diff types of injection and dosage will help to improve the quality, didn't mention the quantity.
 

Zcshop

Member
Your long protocol means injection longer than 10 days?? Mine was 14 days injection because dr said my egg grow slow.. but my tcm practitioner told me normally they only suggest to inkect for 9-11 days.
Long protocol requires u to jab lucrin for abt 14 to 21 days before u can start stim drugs. That said, i think the Dr didnt give me suitable drugs n hence, my egg quality is compromised
 

WhenItComes

New Member
I personally find her overrated - long queues, attitude issues and don’t really work for me. There are other better TCM physicians out there. Then again, it is a personal opinion and experience from seeing her some years ago.
Ok. My appointment with her will be 4 months later!!!!!
 

WhenItComes

New Member
Long protocol requires u to jab lucrin for abt 14 to 21 days before u can start stim drugs. That said, i think the Dr didnt give me suitable drugs n hence, my egg quality is compromised
Actually i did consumed 21 days of progesteron before stim, because dr found 1 big follicle growing before the stim. Then start with 14 days stim. I hope my poor egg quality is due to protocol but not inherent...
 

Hi good afternoon everyone I have been doing ivf for past 2 years but still not getting any good results did 2 fresh and 1 Fet . All at Kk. First fresh Er 17 only 2 make it for Et so I only Et 1 embryo for first time and I got 1 to frozen So sad both also Bpn. And this time third Time for ivf doing fresh had er 14 also only two make it for et dr said this time we try two and I agree. It still my tww but i already feel my menses is coming. So sad I feel like crying and don’t know what when wrong. I already try what I can do taking supplements go Tom acupuncture do yoga and massage and dr recommend me to do scratch test I did, but still don’t get good new. Should I change to other hospitals or stay if I want to try again?
 

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