Anyone doing IVF in 2020?

yy116

Member
Only 15-16k? We got quoted at NUH for 14k already...

Btw, anyone else heard the rumor that NUH will be closed from March 2021 for a renovation?
I asked prof during my last visit in early Nov and he said the budget for the reno is not approve yet. My transfer will be end feb or early march next year=)
 


risther

Member
Hi for KKH fresh cycle, can I ask if anyone were prescribed crinone gel at first for 3 days after ER but in the end no ET is performed? My previous scans show I likely might have a polyp but doc did not confirm with me after ER cos she she say she will check on the lining during ER. I thought if got polyp cannot transfer at all then what’s the purpose for giving me crinone in the first place?
 

Zerelda

Active Member
I think so! I asked Prof PC Wong for Feb cycle next year and he said ok.. I thought the Reno will start from Feb. I’m taking a risk, because if I have OHSS I can’t even do any transfer :(
They shld design a protocol for you that doesn’t make you over stimulate.... I have history of PCOS from 2 years ago so my doctor takes that into account when designing a protocol.
 

Zerelda

Active Member
Do — stay stress free and happy! Rest and eat well. Eat — not sure if it is too late because it is tomorrow but it is actually good to start right from stimms. People say can try durian, brazil nuts, Longan red date tea, red bean soup. I have tried some here and some others but not everything. Then again, it depends on individual.
Yeps.. important to keep the womb warm and promote blood circulation (light walking). No cold drinks for sure. But there’s really no science onto how to make embryo implant... To me, that’s the only unknown in IVF. Cuz you can have a good lining and good quality embryo but it still doesn’t implant. @Babyss
 

SecondEverett

New Member
@SecondEverett PGS/PGT is not available in Singapore? I think Dr Tan Heng Hao uses this for his patients.. It isn’t exactly cheap here in the US too, I paid 1.3k USD for 5 embryos.
Yes pgs is not available in Singapore unless the couple has a genetic condition which requires screening and then they will need to seek approval from MOH. Nearest country this is available in is Malaysia but with covid currently, not possible at the moment I guess. Yes probably he will liaise with the Malaysian side though the fees for transportation of embryos etc can be hefty. So most of us end up not doing pgs at all and just transfer.
 

Zerelda

Active Member
Yes pgs is not available in Singapore unless the couple has a genetic condition which requires screening and then they will need to seek approval from MOH. Nearest country this is available in is Malaysia but with covid currently, not possible at the moment I guess. Yes probably he will liaise with the Malaysian side though the fees for transportation of embryos etc can be hefty. So most of us end up not doing pgs at all and just transfer.
Wow I didn’t know that! I thought Singapore would always have good medical technologies. There are a few types of PGT.. There is PGT-A/PGS that screens for abnormal no. of chromosomes; PGT-M for couples with genetic condition and PGT-R (I think) to detect poor organization or smth... What you mentioned abv sounds like PGT-M which is more troublesome..

PGS/PGT-A will actually save a lot of heartbreak in my opinion... I have a friend who suffered 2 miscarriages and after she opted for PGT-A on all her frozen embryos, she did not have a miscarriage since then (3 children all IVF).
 

Cmf

Member
Yes pgs is not available in Singapore unless the couple has a genetic condition which requires screening and then they will need to seek approval from MOH. Nearest country this is available in is Malaysia but with covid currently, not possible at the moment I guess. Yes probably he will liaise with the Malaysian side though the fees for transportation of embryos etc can be hefty. So most of us end up not doing pgs at all and just transfer.
Hi
Actually singapore did have PGS but I think started not long ago only and I think still under research study but i'm not too sure any changes to it cos i got this info a year ago. And to go through PGS need to meet certain criteria, or fall into one of the three categories:
: Age 35-44 at the start of the IVF cycle
: Have had 2 or not unsuccessful embryos transfers, age 21-44 at the start of IVF cycle
: Have had 2 or more confirmed miscarriage, age 21-44 at the start of IVF cycle

So when they offer me this PGS research. The nurse told us, this is a 50% 50% chances. I might not even have enough embryos to go through the day 5 stages for PGS testing, so I was told by them if i don't have enough embryo to pass through Day 5 stage, embryologist will decide to transfer back early without doing any testing. Or the embryo might not survive through the PGS testing.

And the other concern was the cost for this PGS, I was being told that if the embryo able to go for PGS testing, irregarrdles whether the embryo is able or not able to survive before the transfer. I have to pay $6k in cash. ( Depend how many embryos u have also)

Actually we did asked KKH about this testing before but by then was told that Singapore doesn't have this testing. So when Prof Wong in NUH mentioned about this PGS testing i was quite surprised. I think it was just launched 1 or 2 years ago. N the nurse told me now only NUH, KKH n SGH had this testing and was told that Prof Wong is the head for this programme for these 3 hospitals.

But I didn't go for PGS as i only left one n only precious embryo. Don't want to give up my last chance for ET. :)
 

Zerelda

Active Member
Hi
Actually singapore did have PGS but I think started not long ago only and I think still under research study but i'm not too sure any changes to it cos i got this info a year ago. And to go through PGS need to meet certain criteria, or fall into one of the three categories:
: Age 35-44 at the start of the IVF cycle
: Have had 2 or not unsuccessful embryos transfers, age 21-44 at the start of IVF cycle
: Have had 2 or more confirmed miscarriage, age 21-44 at the start of IVF cycle

So when they offer me this PGS research. The nurse told us, this is a 50% 50% chances. I might not even have enough embryos to go through the day 5 stages for PGS testing, so I was told by them if i don't have enough embryo to pass through Day 5 stage, embryologist will decide to transfer back early without doing any testing. Or the embryo might not survive through the PGS testing.

And the other concern was the cost for this PGS, I was being told that if the embryo able to go for PGS testing, irregarrdles whether the embryo is able or not able to survive before the transfer. I have to pay $6k in cash. ( Depend how many embryos u have also)

Actually we did asked KKH about this testing before but by then was told that Singapore doesn't have this testing. So when Prof Wong in NUH mentioned about this PGS testing i was quite surprised. I think it was just launched 1 or 2 years ago. N the nurse told me now only NUH, KKH n SGH had this testing and was told that Prof Wong is the head for this programme for these 3 hospitals.

But I didn't go for PGS as i only left one n only precious embryo. Don't want to give up my last chance for ET. :)
Yea PGS is a pretty new thing.. About 5 years or so but it is 90% accurate in detecting aneuploidy. In the US.. It is open to anyone as long as you are willing to pay - they count by per embryo or you can buy a package; approximately $200-400 USD per embryo depending on how many you send in. If you want insurance to cover the cost, almost the same requirements as above - 2 miscarriages or more. And yep, because they biopsy a few cells of the day 5/6/7 embryo so embryos that are not “strong” will not make it. Fortunately all 5 of mine did not have any issues after biopsy.. Now I’m just anxiously waiting for the results. I chose to do it because 50% of a woman’s eggs are aneuploid in nature and it gets higher with age. I’m 32 but I see some of my friends around this age also facing miscarriage too (not due to accident) so I decided to go for it.
 
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JOJO_POS

Member
Yes pgs is not available in Singapore unless the couple has a genetic condition which requires screening and then they will need to seek approval from MOH. Nearest country this is available in is Malaysia but with covid currently, not possible at the moment I guess. Yes probably he will liaise with the Malaysian side though the fees for transportation of embryos etc can be hefty. So most of us end up not doing pgs at all and just transfer.
Hi there! Am with SGH for my 2 rounds of ivf and my dr suggested PGS after I have failed my 1st ivf cycle even with good quality embryos. The cost is abt 5k but I didn't take it up.
 

JOJO_POS

Member
Hi all, asking for a friend here. Anyone can share the list of hospitals and clinics offering fresh transfer? Thank you.
SGH offers fresh transfer but Dr needs to check yr hormone level after all the injections first before allowing for fresh transfer. It must be within the acceptable range.
 

Zerelda

Active Member
Hello all, I have 2 bottles of Blue Stork Men Fertility (unopened) and 2 boxes of Revosit (for egg quality), they are all in sachets. If interested, please PM me. I am not selling it and giving it away but you would have to pay for the postage to Singapore.

A little bit of a history, my husband used to take this but he has weak digestion so I had to switch to liquid. I matched his new supplements to Blue Stork. This is the #1 choice for men’s fertility and each bottle costs $35.99 USD on Amazon. Revosit was purchased in Singapore at $50 per box. I used Revosit a week before stimulation started and during my stimulation - I’m unsure if it helped me.. I take prenatal and prenatal omega too. My doctor focused on quality over quantity and triggered me when they scanned 7 potential follicles. 9 were retrieved but 3 were not matured (didn’t reach optimal size yet). All my 6 eggs were 100% fertilized (typically only 50-75%).. All 6 also survived to day 5 which is pretty amazing since 50-80% typically die on day 3. I ended up with 4 grade AA blastocysts and 1 grade BB blastocyst as 1 blastocyst simply stopped growing after day 5. Therefore, my total blastocyst survival rate stands at 83% (usually it’s about 20-50%).

My Infertility Journey documented here: http://eggsofrainbow.wordpress.com
 
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SecondEverett

New Member
Hi
Actually singapore did have PGS but I think started not long ago only and I think still under research study but i'm not too sure any changes to it cos i got this info a year ago. And to go through PGS need to meet certain criteria, or fall into one of the three categories:
: Age 35-44 at the start of the IVF cycle
: Have had 2 or not unsuccessful embryos transfers, age 21-44 at the start of IVF cycle
: Have had 2 or more confirmed miscarriage, age 21-44 at the start of IVF cycle

So when they offer me this PGS research. The nurse told us, this is a 50% 50% chances. I might not even have enough embryos to go through the day 5 stages for PGS testing, so I was told by them if i don't have enough embryo to pass through Day 5 stage, embryologist will decide to transfer back early without doing any testing. Or the embryo might not survive through the PGS testing.

And the other concern was the cost for this PGS, I was being told that if the embryo able to go for PGS testing, irregarrdles whether the embryo is able or not able to survive before the transfer. I have to pay $6k in cash. ( Depend how many embryos u have also)

Actually we did asked KKH about this testing before but by then was told that Singapore doesn't have this testing. So when Prof Wong in NUH mentioned about this PGS testing i was quite surprised. I think it was just launched 1 or 2 years ago. N the nurse told me now only NUH, KKH n SGH had this testing and was told that Prof Wong is the head for this programme for these 3 hospitals.

But I didn't go for PGS as i only left one n only precious embryo. Don't want to give up my last chance for ET. :)
Yes u r right .. only NUH offers it but more like a trial where they will take the data for research etc.. but private clinics which I go to all don’t have this option unfortunately.. hopefully the government will review this.
 

mewtwo

New Member
We just received a call from NUH. They booked for us an appointment on December 22nd for consultation. That is quite crazy for 1 month of waiting just for consultation.

Here is the problem: dr Stephen gave us a list of medication to start once we talk to CHR nurses. The brochure says we should start them on 18th of the period cycle. But December 22nd will be my 22nd day for the next cycle already.

Anyone else having the extremely long waiting time for the first consultation with CHR nurse? Do you have to take medication starting from day 18 of the previous period? What would be the problem if starting late? What should we do?

pls help!
 
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SecondEverett

New Member
Hello all, I have 2 bottles of Blue Stork Men Fertility (unopened) and 2 boxes of Revosit (for egg quality), they are all in sachets. If interested, please PM me. I am not selling it and giving it away but you would have to pay for the postage to Singapore.

A little bit of a history, my husband used to take this but he has weak digestion so I had to switch to liquid. I matched his new supplements to Blue Stork. This is the #1 choice for men’s fertility and each bottle costs $35.99 USD on Amazon. Revosit was purchased in Singapore at $50 per box. I used Revosit a week before stimulation started and during my stimulation - I’m unsure if it helped me but I have 4 grade AA blastocysts and 1 grade BB blastocyst. All my 6 eggs were 100% fertilized. My doctor focused on quality over quantity and triggered me when they scanned 7 potential follicles. 9 were retrieved but 3 were not matured (didn’t reach optimal size yet).

My Infertility Journey documented here: http://eggsofrainbow.wordpress.com
Your results of your blasts are really good..I think your protocol and clinic must be v experienced and advanced. I heard and read that US is at the forefront of ivf.. you are lucky to be able to do it over there. wishing you all the best in your transfer!! Positive and sticky vibes to you babe!
 

Zerelda

Active Member
We just received a call from NUH. They booked for us an appointment on December 22nd for consultation. That is quite crazy for 1 month of waiting just for consultation.

Here is the problem: dr Stephen gave us a list of medication to start once we talk to CHR nurses. The brochure says we should start them on 18th of the period cycle. But December 22nd will be my 25th day for the next cycle already.

Anyone else having the extremely long waiting time for the first consultation with CHR nurse? Do you have to take medication starting from day 18 of the previous period? What would be the problem if starting late? What should we do?

pls help!
Then you will just need to wait for your next cycle.. He gave medication or vitamins? I don’t think you will get any ivf medication until all the bloodwork is done. Therefore there isn’t really a starting late or early.. Moreover, after your first consultation, you will have a series of tests to do.

I rmbed when I had my first appt, I was on my 2nd day of period. So I had to wait till my next period that took like 40 days (I’m irregular).. and then do the blood tests on day 2 of menses... Only after that I had my first scan with the doctor... After the scan....i was put on bcp to time it.. medication started with overlap of last 4 days bcp.

You can take this time to prep your body, start on your vitamins. Having good eggs and sperm starts from before stimulation.

You can read about my journey here: http://eggsofrainbow.wordpress.com (I have a food menu there that’s designed in collaboration with my nutritionist based on food I eat).
 

Zerelda

Active Member
T
Yes u r right .. only NUH offers it but more like a trial where they will take the data for research etc.. but private clinics which I go to all don’t have this option unfortunately.. hopefully the government will review this.
The government will really need to review this in order to prevent more ivf failures.. I have quite a number of friends and colleagues in the United States who have healthy live births only after they did PGT-A/PGS. But that’s at the expense of 1-2 miscarriages
 

najnaj

Member
Will genetic screening helps to overcome implantation failures? I just failed my 4th FET. Among 4, all bfn, except one with chemical pregnancy. All of my embryos r quite good blastocysts. I only left with another 2 to go.
My most recent one is my first attempt on natural FET, I quite like the overall experience as I do not suffer from d side effects of progynova n phobia of inserting estrofen. Lining seems to respond better too. This time round, I transferred 2 day 6 blastocysts. My ovulation should b day 14 based on blood test, n the transfer is on day 21. Crinone gel started on day 16 onwards. But I m reading normally, ET is 5 or 6d after ovulation. So wondering if I missed the optimal window this time. And another qns, I m now left with one day 5 n one day 6 blastocysts. Can transfer both d5 n d6 blastocysts at once ?
 

Zerelda

Active Member
Will genetic screening helps to overcome implantation failures? I just failed my 4th FET. Among 4, all bfn, except one with chemical pregnancy. All of my embryos r quite good blastocysts. I only left with another 2 to go.
My most recent one is my first attempt on natural FET, I quite like the overall experience as I do not suffer from d side effects of progynova n phobia of inserting estrofen. Lining seems to respond better too. This time round, I transferred 2 day 6 blastocysts. My ovulation should b day 14 based on blood test, n the transfer is on day 21. Crinone gel started on day 16 onwards. But I m reading normally, ET is 5 or 6d after ovulation. So wondering if I missed the optimal window this time. And another qns, I m now left with one day 5 n one day 6 blastocysts. Can transfer both d5 n d6 blastocysts at once ?
Most of the time when IVF fails (failure to implant or miscarriage not due to accident), it is usually due to aneuploidy (only can be tested via PGT-A/PGS). A grade AA blastocyst can also be aneuploid. Statistically, 50% of the woman’s eggs in her life time are aneuploid (gets higher with age). Of course, this is when the woman is also absent of endometrium issues (needs to be at least 8mm) and other health issues.

The grading of the blastocyst is only related to the inner cell mess and the trophectoderm, nothing to do with chromosomes.
 

mewtwo

New Member
Then you will just need to wait for your next cycle.. He gave medication or vitamins? I don’t think you will get any ivf medication until all the bloodwork is done. Therefore there isn’t really a starting late or early.. Moreover, after your first consultation, you will have a series of tests to do.

I rmbed when I had my first appt, I was on my 2nd day of period. So I had to wait till my next period that took like 40 days (I’m irregular).. and then do the blood tests on day 2 of menses... Only after that I had my first scan with the doctor... After the scan....i was put on bcp to time it.. medication started with overlap of last 4 days bcp.

You can take this time to prep your body, start on your vitamins. Having good eggs and sperm starts from before stimulation.

You can read about my journey here: http://eggsofrainbow.wordpress.com (I have a food menu there that’s designed in collaboration with my nutritionist based on food I eat).
Dr Chew gave us a prescription that includes Norethisterone and Andriol and told us to buy it once we consult with CHR nurses.
What we don't understand is whether we will start the scan/injection right after the consultation (which is January) or we will have to wait until Feb 2021?
 

fyz

New Member
Hi all, Happy New Year 2020!
I would like your opinions on iui/ivf.
I have pcos and was put on clomid for several rounds (unsuccessful for all). I just did the HSG test and my tubes are clear. I am below 30 years old and am really inclined to try iui first (age factor, etc). But my hubs suggested going for ivf straightaway.

I’ll seek advice from my gynae on my next appt, but would really like to hear other input as well. Should i try iui first or go straight to ivf? Thanks in advance!
Hello dear,
I have pcos as well and I am below 30 too!and Ive been TTC for 3 years. I tried SO-IUI twice and both unsuccesful. And now the doc straightaway put me for IVF. Currently, im on day 3 of self injection..while waiting for my egg retrieval, which will be on 2nd of dec 2020, I will try my best to lose weight as I heard it helps.

Wishing you all the best and baby dust to us all❤
 

Zerelda

Active Member
Hello dear,
I have pcos as well and I am below 30 too!and Ive been TTC for 3 years. I tried SO-IUI twice and both unsuccesful. And now the doc straightaway put me for IVF. Currently, im on day 3 of self injection..while waiting for my egg retrieval, which will be on 2nd of dec 2020, I will try my best to lose weight as I heard it helps.

Wishing you all the best and baby dust to us all❤
I had PCOS previously too but I got rid of it prior to IVF (lifestyle changes and getting rid of toxins). I don’t think you can lose weight in just a few days, the most important thing now will be to ensure you get all the right nutrients for your eggs (nutritious food, prenatal etc etc). Good luck.



 
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Zerelda

Active Member
Will genetic screening helps to overcome implantation failures? I just failed my 4th FET. Among 4, all bfn, except one with chemical pregnancy. All of my embryos r quite good blastocysts. I only left with another 2 to go.
My most recent one is my first attempt on natural FET, I quite like the overall experience as I do not suffer from d side effects of progynova n phobia of inserting estrofen. Lining seems to respond better too. This time round, I transferred 2 day 6 blastocysts. My ovulation should b day 14 based on blood test, n the transfer is on day 21. Crinone gel started on day 16 onwards. But I m reading normally, ET is 5 or 6d after ovulation. So wondering if I missed the optimal window this time. And another qns, I m now left with one day 5 n one day 6 blastocysts. Can transfer both d5 n d6 blastocysts at once ?
@najnaj I have 2 posts on PGT and aneuploidy just in case you wanted to read more. From the posts above, PGT-A is still very limited in Singapore (and expensive) therefore do talk to your doctor on options.


 

Zerelda

Active Member
Your results of your blasts are really good..I think your protocol and clinic must be v experienced and advanced. I heard and read that US is at the forefront of ivf.. you are lucky to be able to do it over there. wishing you all the best in your transfer!! Positive and sticky vibes to you babe!
I’m still waiting for the PGT-A results, I’m hoping the fresh transfer I did was a euploid blast, we didn’t want to wait and went ahead with the best looking blast (partially hatched). However, best looking might not mean Euploid. My doctor didn’t recommend for me to do PGT-A but I wanted to do it cuz of 2 friends’ exp. However, this is only 1 part of the equation to try and get things right.

Implantation and uterine receptivity are still huge questions in science, hopefully I’ve some luck for my blast to stick . But I’ve been having zero symptoms and don’t feel anything which is making me feel extremely anxious today. No cramps, no spotting, no more painful/sensitive boobs, don’t even feel tired/fatigue, not nauseous...
 
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Zerelda

Active Member
Your results of your blasts are really good..I think your protocol and clinic must be v experienced and advanced. I heard and read that US is at the forefront of ivf.. you are lucky to be able to do it over there. wishing you all the best in your transfer!! Positive and sticky vibes to you babe!
I’m actually doing the most common protocol in the US as my blood work and health checks didn’t detect any anomalies except longer luteal phases where bcp is used to control/time. On the other hand, it turns out that it could possibly be a male factor since my husband’s sperms has a huge variance. It is called the antagonist protocol that uses lupron (10 units before fsh and lh introduced, thereafter 5 units), gonal-f (300iu) and menopur (150iu). My clinic does have some pretty decent track record that’s slightly higher so hopefully my dream will finally come through
 

Zerelda

Active Member
Dr Chew gave us a prescription that includes Norethisterone and Andriol and told us to buy it once we consult with CHR nurses.
What we don't understand is whether we will start the scan/injection right after the consultation (which is January) or we will have to wait until Feb 2021?
Usually need to wait.. stimulation will only start when your progesterone and estrogen levels are both low, usually start stimulation day 2-4 of your cycle.. but prior to starting stims, will start you on an injection to prevent premature ovulation (I was using lupron; other drugs used are oruglutan and ganirelix)
 

SecondEverett

New Member
I’m actually doing the most common protocol in the US as my blood work and health checks didn’t detect any anomalies except longer luteal phases where bcp is used to control/time. On the other hand, it turns out that it could possibly be a male factor since my husband’s sperms has a huge variance. It is called the antagonist protocol that uses lupron (10 units before fsh and lh introduced, thereafter 5 units), gonal-f (300iu) and menopur (150iu). My clinic does have some pretty decent track record that’s slightly higher so hopefully my dream will finally come through
Yes I read abt this protocol that is commonly used in the states. Not sure why sg doesn’t follow it..
 

Zerelda

Active Member
T
Yes I read abt this protocol that is commonly used in the states. Not sure why sg doesn’t follow it..
There are actually a few more other protocols that I see in my book but they determine which protocol to use from bloodwork. I think Singapore does differently in many things because most of the doctors are locally trained under different regimes and Singapore leads its own research function. Also Singapore probably has a smaller ivf group to conduct any studies when compared to the US (over 200k ivf procedures annually).
 

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