for tigerbaby
What is SO-IUI?
SO – Super Ovulation (where fertility drugs are given to increase the follicle growth)
IUI – Intrauterine insemination (where sperms are washed and placed directly into the uterus to increase chances of conception)
SO-IUI can be done by fertility specialists in all major hospitals in Singapore. The procedure itself is relatively less complex as compared to IVF.
Prep for procedure
Prior to the procedure, fertility specialists will normally encouraged the patients to do an Sperm Analysis (SA) test for hubby and for ladies HSG test (to check fallopian tube blockage) and blood test (to test the various hormones level) to ensure that you are a suitable candidate for SO-IUI.
Days before your anticipated menstrual cycle, patients who are embarking on the procedure will be asked to go down to the clinic to collect the fertility drugs (normally Gonal-F or Puregon will be given) and will be taught on the injection procedure. On top of that, you will be given the injection pen.
The injections will be done by patients themselves and the drugs have to be injected everyday at the same time.
You will also need to bring down your marriage cert, IC to the doctor for verification and to sign consent forms.
Simplified procedure steps
Day 1 of menstruation cycle – injection of Puregon (lowest dosage of 75iu). Doctors will normally start patients with the lowest Puregon dosage.
In Singapore, the maximum number of follicles allowed for SO-IUI is 4 eggs, anything more fertility specialists might recommend to convert to IVF
Day 5 of menstruation cycle – To go back to clinic to scan the follicle growth, if the eggs are responding to the injectibles, the doctor will increase the dosage of the Puregon to stimulate the follicles to grow to the ideal size. The uterus lining will also be checked.
Day 8 of menstratuation cycle – To go back to clinic again to check the follicle growth size, once the follicles reached the ideal size of about 18mm, the doctor will advise patients on the time of the HCG shot. The HCG shot is done to force ovulation to take place.
Pls note that the day of the injection and scan will be advised by doctors, the above is just the rough guide
After the injection of the HCG shot, patients will be advised again by doctor on the day to return for the insemination.
Insemination day
Hubbies got to produce a fresh sample of semen for the hospital. Recommended to produce sample at hospital to keep it fresh.
The lab will collect the sample and sperms are "washed" to segregate out the best sperms for inserting back to the uterus. The final best sperms will be given a dose of drugs to make them more powerful swimmers.
Once the sperms have been washed, the doctor will then placed the sperms into the uterus via a fine catheter. The procedure itself is not painful at all, in fact I don’t feel anything when the sperms are injected.
After the insemination of the sperms, the patient will be asked to rest in the hospital for ½ hour or so and you will be allowed to return home. The patient will be asked by the doctor to start medications (progesterone) to help improved the implantation and thus pregnancy. A blood test will be done 14 days later to check whether you are preggie Good luck ~
Cost of procedure
The procedure itself will cost about 1.8K depending on hospitals. Procedure can be claimed using Medisave but in Singapore, the max claim for assisted reproductive techniques (ART) is 3 times for both IUI/IVF. Therefore pls think carefully whether you want to waste the claim for SO-IUI
Success rates
The average success rate is about 12 to 15 per cent per cycle, or 26 per cent per patient after three cycles. The overall success rate varies with the cause of infertility and the age of the female partner. For some conditions, the pregnancy rate can be as high as 36 per cent per patient.