IVF/ICSI Support Group

ding2505

Active Member
Ya, it's harder to get donor eggs cos it means the lady who is willing to help you has to undergo injections and egg retrieval. It's a tough job and I don't think most women would want to go through the pain just to donate.

Perhaps you can try donor embryos - couples who are done with having children, but still have frozen embryos.

If you cant find any couple who is willing to donate their embryos, you may want to consider adoption to fulfil your dream to be a mother.
That’s true, you are very right. Even for ourselves to go through all the jabs and all it’s so tough alr how to ask people to go through it? Embryos or adoption is easier.

But Aries have you asked the doctor whether egg quality can be improved? Or maybe change of diet and exercise? If it is not a genetic issue I believe we can change our bodies if we have a will.
 


towkayneo

Well-Known Member
That’s true, you are very right. Even for ourselves to go through all the jabs and all it’s so tough alr how to ask people to go through it? Embryos or adoption is easier.

But Aries have you asked the doctor whether egg quality can be improved? Or maybe change of diet and exercise? If it is not a genetic issue I believe we can change our bodies if we have a will.
I think she mentioned age as a factor.

Yeah, I think 2 years back, I happened to see a posting of donor embryos. This guy is done with family planning, and he didn't want to waste the balanced embryos, so he donated.
 
I think she mentioned age as a factor.

Yeah, I think 2 years back, I happened to see a posting of donor embryos. This guy is done with family planning, and he didn't want to waste the balanced embryos, so he donated.
Hope there is a kind hearted person lend me a hand in order to have a chance to be mother ! Just feeling sad everyday I think of it , feeling loss my motivation and goal !
 

littlemonkies

Well-Known Member
Hope there is a kind hearted person lend me a hand in order to have a chance to be mother ! Just feeling sad everyday I think of it , feeling loss my motivation and goal !
Aries, will your husband agree to donor embryo? Will both of you mind that the baby will not bear your genetic make up?
 

Dreamscometrue

Well-Known Member
Hope there is a kind hearted person lend me a hand in order to have a chance to be mother ! Just feeling sad everyday I think of it , feeling loss my motivation and goal !
I guess we are in no position to say this but life is more than having babies.. though not many, but its getting common that married couples have no kids.
If u have kids when too old, various risk is also much much higher. And when you're into 70s, your kid probably still schooling.. just my thought la
Nonetheless its a choice and decision to be made. Hope you will find an answer and peace soon. Feeling sad everyday is not going to help you in anyway. Stay strong!
 

milogal88

Well-Known Member
Hope there is a kind hearted person lend me a hand in order to have a chance to be mother ! Just feeling sad everyday I think of it , feeling loss my motivation and goal !
Having a child is not a bed of roses. The challenges are A LOT tougher than the TTC journey itself. Infact, I remember breaking down in front of my doc then (Dr Tan HH) when I went for a usual review coz it was just super overwhelming after the kids came along. I used to think like you....feeling sad & depressed not having kids and I even sought psychiatric help. But I guess as time goes by like what @Dreamscometrue mentioned, life is more than just having babies. I guess without such expectations, my emotional state was better and might be a factor that we managed to succeed eventually. Don't stress about it too much. Hugs.
 
That’s true, you are very right. Even for ourselves to go through all the jabs and all it’s so tough alr how to ask people to go through it? Embryos or adoption is easier.

But Aries have you asked the doctor whether egg quality can be improved? Or maybe change of diet and exercise? If it is not a genetic issue I believe we can change our bodies if we have a will.
If you have low overran reserv
Aries, will your husband agree to donor embryo? Will both of you mind that the baby will not bear your genetic make up?
Hi sisters ! To get donor eggs is so difficult in Singapore don’t said embryo even more difficult ! Feeling sad when see couples carry baby outing but we are unable to have this sense of happiness on it !
 
Having a child is not a bed of roses. The challenges are A LOT tougher than the TTC journey itself. Infact, I remember breaking down in front of my doc then (Dr Tan HH) when I went for a usual review coz it was just super overwhelming after the kids came along. I used to think like you....feeling sad & depressed not having kids and I even sought psychiatric help. But I guess as time goes by like what @Dreamscometrue mentioned, life is more than just having babies. I guess without such expectations, my emotional state was better and might be a factor that we managed to succeed eventually. Don't stress about it too much. Hugs.
Whenever we go outing seeing couples carrying babies , my heart feel very very upset . I don’t have a chance to hear my baby called me mummy ! This is the most regret in my life! As what the doctor said my overian is very Low unless donor eggs . Whenever I think of it I feel very very upset !
 

Dreamscometrue

Well-Known Member
Having a child is not a bed of roses. The challenges are A LOT tougher than the TTC journey itself. Infact, I remember breaking down in front of my doc then (Dr Tan HH) when I went for a usual review coz it was just super overwhelming after the kids came along. I used to think like you....feeling sad & depressed not having kids and I even sought psychiatric help. But I guess as time goes by like what @Dreamscometrue mentioned, life is more than just having babies. I guess without such expectations, my emotional state was better and might be a factor that we managed to succeed eventually. Don't stress about it too much. Hugs.
Hi it has been a long time since last saw u here again. Are u going for another baby?
 

milogal88

Well-Known Member
Whenever we go outing seeing couples carrying babies , my heart feel very very upset . I don’t have a chance to hear my baby called me mummy ! This is the most regret in my life! As what the doctor said my overian is very Low unless donor eggs . Whenever I think of it I feel very very upset !
Hugs. Certain things are beyond our control but as long as we tried & exhaust most avenues, give yourself a pat on the back. Is this your 1st IVF? have you tried TCM or seen a 2nd opinion for your low ovarian reserves? one of my frens also similar case and while waiting for IVF to start, she strike naturally & her girl is 1yo. I still remember her very despaired look when she shared with us she's like almost menopause kind of stage as she was 40yo then.
 

Dreamscometrue

Well-Known Member
Whenever we go outing seeing couples carrying babies , my heart feel very very upset . I don’t have a chance to hear my baby called me mummy ! This is the most regret in my life! As what the doctor said my overian is very Low unless donor eggs . Whenever I think of it I feel very very upset !
Any relatives willing to donate their eggs? Maybe can try
 

cloudxy

Member
Adoption was something my husb and I considered if we're unable to have our own child. And if we were to adopt, we were looking at adopting through MSF instead of paying agencies a hefty fee for it.

It felt like since we want to have a child, why not help one who needs a home instead of "buying" one? But of course, it may be easier said than done as we both have to be sure that we're ready to open our hearts for this.

So why not let this be an option as well? :)
 

Dreamscometrue

Well-Known Member
Adoption was something my husb and I considered if we're unable to have our own child. And if we were to adopt, we were looking at adopting through MSF instead of paying agencies a hefty fee for it.

It felt like since we want to have a child, why not help one who needs a home instead of "buying" one? But of course, it may be easier said than done as we both have to be sure that we're ready to open our hearts for this.

So why not let this be an option as well? :)
Hi u BFP right. Any symptoms during the tww?
 

littlemonkies

Well-Known Member
Whenever we go outing seeing couples carrying babies , my heart feel very very upset . I don’t have a chance to hear my baby called me mummy ! This is the most regret in my life! As what the doctor said my overian is very Low unless donor eggs . Whenever I think of it I feel very very upset !
I know what you mean. When my friends got pregnant last time, I felt really horrible when I felt more jealous than happy for them. Seeing people with kids also made me feel so sad for myself. It's natural for women to feel these way because we are biologically driven to want kids.

Actually no harm asking your doctor how to go about getting embryo donations. There may be some who have quite a number, but don't have energy to go through another round of pregnancy. I don't think it's impossible.

Or try fostering/adoption
 

Angelica Cheng

Active Member
Any relatives willing to donate their eggs? Maybe can try
Here are the various fractions of DNA that you would share with your child, with different types of blood relatives as egg donor:

Full sister - 25% (1/4)

Half-sister or niece - 12.5% (1/8)

First cousin - 6.25% (1/16)


Second cousin - 3.125% (1/32).

Note that if you were using your own eggs, you would share 50% (1/2) of DNA with your child.
 
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Dreamscometrue

Well-Known Member

Here are the various fractions of DNA that you would share with your child, with different types of blood relatives as egg donor:

Full sister - 25% (1/4)

Half-sister or niece - 12.5% (1/8)

First cousin - 6.25% (1/16)

Second cousin - 3.125% (1/32).

Note that if you were using your own eggs, you would share 50% (1/2) of DNA with your child.
Thanks for sharing..
 

cloudxy

Member
Hi u BFP right. Any symptoms during the tww?
Yes, after trying for about 2 years or so. It's from a fresh cycle and also our last chance because I have no frozen and only 1 embryo that could be transferred. We've also more or less used up the MediSave allowable so we didn't dare to place too much hopes on this last chance.

I started getting hungry more often in the 2nd week, boobs getting more tender and was also very tired. But I didn't dare to think it was a BFP coz it could have also been the progesterone I was on. We're really lucky after a blighted ovum last year and I was nervous and scared until the first ultrasound.
 

Dreamscometrue

Well-Known Member
Yes, after trying for about 2 years or so. It's from a fresh cycle and also our last chance because I have no frozen and only 1 embryo that could be transferred. We've also more or less used up the MediSave allowable so we didn't dare to place too much hopes on this last chance.

I started getting hungry more often in the 2nd week, boobs getting more tender and was also very tired. But I didn't dare to think it was a BFP coz it could have also been the progesterone I was on. We're really lucky after a blighted ovum last year and I was nervous and scared until the first ultrasound.
What u did during the tww?
 

Angelica Cheng

Active Member
Can donor egg recipients 'pass on DNA' to their children? - BioNews

2 November 2015
By Dr Jess Buxton
Geneticist, University College London
Appeared in BioNews 826
The idea that environmental conditions in the womb may have long-lasting effects on development and future health is well-established. We have known for some time, for example, that low birthweight is linked to an increased risk of type 2 diabetes and heart disease in adulthood. The search for biological culprits that might underpin this and similar observations is a highly active area of research, a field known as DOHaD (developmental origins of health and disease). One promising line of enquiry is epigenetics, the study of enduring changes in gene activity. Through epigenetic alterations, the activity levels of some genes may be turned up – or down – in response to external cues present in our environment. This includes our first environment, the womb.

How early on in development might such changes occur? A recent study suggests that embryonic gene activity may be altered by factors present in the womb even before implantation. This finding triggered a somewhat misleading newspaper article entitled 'Infertile mums "pass on DNA"', which claimed the research means recipients of donor eggs are passing on their own DNA to their child. This isn't the case. But the scientists did discover a way in which women who conceive using donor eggs may affect the activity of their child's genes, from the earliest stages of pregnancy onwards.

The research team, based in Spain and the USA, studied molecules called microRNAs (1). As the name suggests, microRNAs are short sections of RNA, a chemical relative of DNA. Their job is to fine-tune the activity levels of genes during development and throughout life. As such, they are key part of the epigenetic machinery. MicroRNAs, like proteins, are themselves the products of genes - there are over 2500 known human microRNA genes. Each microRNA is predicted to have hundreds to thousands of different target genes, enabling them to influence complex networks of gene activity in processes ranging from growth and development to immunity.

The researchers first identified a set of microRNAs present in the nurturing fluid produced by the womb lining, specifically during the crucial 'window of implantation' – the time when the womb is most receptive to an embryo. They then focused on one particular microRNA, called hsa-miR-30d, which they studied further in mice. They found that after it is released by the womb lining, it is taken up into the embryo before implantation. The team then showed that the activity of several genes was 'turned up' in mouse embryos that had taken up the microRNA, compared to those that hadn't.

If confirmed by other teams, and if a similar effect of the microRNA is demonstrated in humans, then this would be a novel epigenetic mechanism through which the mother's genetic material appears to be influencing the activity of some of the embryo's genes. If each of our 20,000 or so protein-coding genes is thought of as having a 'dimmer' type switch, rather than a simple on/off switch, then the study shows that some switches may get turned up or down a bit just before implantation, in response to levels of hsa-miR-30d. However, what this might mean in terms of its effect on subsequent development of the embryo, or the future health of the resulting child, is unknown. As is often the case, more research is needed.

So the answer to the question 'Can donor egg recipients "pass on DNA" to their children?' is no. But can women who conceive using donor eggs affect their children's genes? Absolutely, as can those who conceive naturally. There is already plenty of evidence to support the beneficial effects of a healthy lifestyle during pregnancy on the developing fetus. And our experiences and environment continue to influence gene activity throughout our lives. What the new research shows is that the influence of the environment in the womb may start even earlier than previously realised.
 

ding2505

Active Member
Help~ am having OHSS, super ultra bloated tummy. Very uncomfortable.. what can I do to lessen the symptoms besides isotonic drink and eggs? Have been having both for the past two days.
 

Blurple

Member
Hi ladies, can i check if anyone finds it more difficult to insert utrogestan after ET? It feels like the vagina wall is tighter?
 

cloudxy

Member
What u did during the tww?
Was in bed a lot for the first 2 days. Then the rest of it was playing games on my laptop, gone for a facial, eat and sleep whenever I felt like it. Even had a couple of cold drinks towards the end of the tww because of the weather. But nothing really special.
 

Dreamscometrue

Well-Known Member
Was in bed a lot for the first 2 days. Then the rest of it was playing games on my laptop, gone for a facial, eat and sleep whenever I felt like it. Even had a couple of cold drinks towards the end of the tww because of the weather. But nothing really special.
Did u like go shopping etc?
 

littlemonkies

Well-Known Member
Help~ am having OHSS, super ultra bloated tummy. Very uncomfortable.. what can I do to lessen the symptoms besides isotonic drink and eggs? Have been having both for the past two days.
Aiyo... have you called the clinic to ask? If I'm not wrong, it's usually conservative treatment - just water and rest
 

towkayneo

Well-Known Member
Help~ am having OHSS, super ultra bloated tummy. Very uncomfortable.. what can I do to lessen the symptoms besides isotonic drink and eggs? Have been having both for the past two days.
It's very normal. It took me at least 5-6 days for the pain to come down and i am talking about extraction of 17 eggs :( I dont recall suffering for so many days during my younger days. It must be age.

The best you can do is to keep drinking water and eating protein as well as Carboline. 4 tiny tablets that cost $70 and each night you take 1/2. Did the doc prescribe that to you?
 

towkayneo

Well-Known Member
Whenever we go outing seeing couples carrying babies , my heart feel very very upset . I don’t have a chance to hear my baby called me mummy ! This is the most regret in my life! As what the doctor said my overian is very Low unless donor eggs . Whenever I think of it I feel very very upset !
Aiya, instead of keep lamenting you are sad and you know it's like so impossible to get donor eggs, why not you do some research and try 1. Donor Embryos 2. Adoption 3. If you insist, donor eggs.

More useful ley.
 

ding2505

Active Member
It's very normal. It took me at least 5-6 days for the pain to come down and i am talking about extraction of 17 eggs :( I dont recall suffering for so many days during my younger days. It must be age.

The best you can do is to keep drinking water and eating protein as well as Carboline. 4 tiny tablets that cost $70 and each night you take 1/2. Did the doc prescribe that to you?
Ya doctor gave me Carboline. Today finally finally the symptoms abated a little, previously stomach was bloated like a balloon or 4 months preggy

Can I check with you ladies how many times do you need to insert crinoline per day? I got prescribed twice a day which I really think is over kill?
 

ding2505

Active Member
Aiya, instead of keep lamenting you are sad and you know it's like so impossible to get donor eggs, why not you do some research and try 1. Donor Embryos 2. Adoption 3. If you insist, donor eggs.

More useful ley.
Agree with towkayneo.
Actually embryos are probably easier to get than eggs in Singapore, because we allow the freezing of embryos but not eggs ( unless for medical reasons) . You should check that out.
At the same time don’t give up hope and keep on tiao li your body! Change doctors if necessary to get a second opinion!
 

claire21

Member
Ya doctor gave me Carboline. Today finally finally the symptoms abated a little, previously stomach was bloated like a balloon or 4 months preggy

Can I check with you ladies how many times do you need to insert crinoline per day? I got prescribed twice a day which I really think is over kill?
True, using it even once was so irritating after initial few days:confused:.... I was also told to use it twice a day & with a gap of 12 Hrs between them.
 

Angelica Cheng

Active Member
Agree with towkayneo.
Actually embryos are probably easier to get than eggs in Singapore, because we allow the freezing of embryos but not eggs ( unless for medical reasons) . You should check that out.
At the same time don’t give up hope and keep on tiao li your body! Change doctors if necessary to get a second opinion!
Actually, not so difficult to find donor eggs in Singapore, just a bit pricey. Please refer to the following links:



 
Aiya, instead of keep lamenting you are sad and you know it's like so impossible to get donor eggs, why not you do some research and try 1. Donor Embryos 2. Adoption 3. If you insist, donor eggs.

More useful ley.
Hi sisters! Thanks for everything ! To get donor eggs is so difficult not said about embryo! Just praying hard there is a kind hearted person lend me a hand to be the donor ! Let me have a chance to be a mother ! Of course I still feeling sad in my heart whenever I think of it ! Just praying to Buddha there is a kind hearted person to be the egg donor !
 

Dreamscometrue

Well-Known Member
Hi sisters! Thanks for everything ! To get donor eggs is so difficult not said about embryo! Just praying hard there is a kind hearted person lend me a hand to be the donor ! Let me have a chance to be a mother ! Of course I still feeling sad in my heart whenever I think of it ! Just praying to Buddha there is a kind hearted person to be the egg donor !
U can go pte clinic and ask if can import donor eggs from other countries. In SG we can tell u is VERY LOW possibility
 

colcol

New Member
Hi sisters! I am already 49. Doctor said unless got donor egg even do IVF success rate not high. Feeling sad when the doctor said this . If I do , can I eat fruits from the fridge Bec they said the injection medication will cause bloatness .
I think you leave it out for awhile before eating the fruits. Cold is not so good. If you really want a child, just try it. At least you tried, your best. Good luck!
 

Angelica Cheng

Active Member
U can go pte clinic and ask if can import donor eggs from other countries. In SG we can tell u is VERY LOW possibility
Actually, I rang up Alpha IVF (Singapore branch) recently. They told me that they are permitted to import frozen donor eggs from Egg Bank Asia based in Penang. Egg Bank Asia is closely affiliated with Island Fertility Centre in Georgetown, Penang.

Here is the Catalogue of Chinese Egg Donors from Egg Bank Asia.
Please see attached PDF file.

Alternatively, you can logon to their website as follows:
https://www.eggbankasia.com/donor-profiles
Username: guest
Password: eba2019
 

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Memegal

New Member
Ya doctor gave me Carboline. Today finally finally the symptoms abated a little, previously stomach was bloated like a balloon or 4 months preggy

Can I check with you ladies how many times do you need to insert crinoline per day? I got prescribed twice a day which I really think is over kill?
Hi Ding2505, have you done your egg retrieval? When did you realise you have OHSS? I have injected 3 days of puregon and am feeling sore all over and a bit bloated.
 

ding2505

Active Member
Hi Ding2505, have you done your egg retrieval? When did you realise you have OHSS? I have injected 3 days of puregon and am feeling sore all over and a bit bloated.
Only after ER then realise.
I think sore and bloated during injections is normal. You only got puregon? I have needle phobia now cos need to inject 3 needles a day the last few days omg.
 

towkayneo

Well-Known Member
Ya doctor gave me Carboline. Today finally finally the symptoms abated a little, previously stomach was bloated like a balloon or 4 months preggy

Can I check with you ladies how many times do you need to insert crinoline per day? I got prescribed twice a day which I really think is over kill?
I have yet to undergo ET, then again, there must be a reason why the doc prescribed 2x crinone for you. just follow bah
 

Dreamscometrue

Well-Known Member
Ya doctor gave me Carboline. Today finally finally the symptoms abated a little, previously stomach was bloated like a balloon or 4 months preggy

Can I check with you ladies how many times do you need to insert crinoline per day? I got prescribed twice a day which I really think is over kill?
Did u mean crinone? Is it ur 1st transfer? Most of the time the doc prescribed 2x a day. At least for my case
 

Memegal

New Member
Only after ER then realise.
I think sore and bloated during injections is normal. You only got puregon? I have needle phobia now cos need to inject 3 needles a day the last few days omg.
Yup, only got puregon 125mg per day now, tml going for follicles scan. As and when will be bloated and legs feel a lot of the water retention. I read that eating more salty food will help besides isotonic drink and eggs.
 


Dreamscometrue

Well-Known Member
Yup, only got puregon 125mg per day now, tml going for follicles scan. As and when will be bloated and legs feel a lot of the water retention. I read that eating more salty food will help besides isotonic drink and eggs.
I think increased salt in your body will cause more water retention.. u may wanna check on this again
 

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