Angelica Cheng
Active Member
In USA, Europe and Australasia, there are rigorous and high standards for genetic screening of prospective Egg Donors (blood sample), before they are even allowed to donate, which largely negate the requirement for recipient patients to use expensive preimplantation genetic screening ( PGS / PGT-A ) to check for potential genetic defects in embryos.
Unfortunately, such rigorous high standards are often not followed by IVF clinics in Malaysia. Instead of genetic testing of the donor's blood sample, patients are strongly encouraged and pushed to opt for more expensive PGS or PGT-A to check for potential genetic defects in embryos. This constitutes an "extra hidden costs" element for overseas egg donation in Malaysia. So when IVF clinics in Malaysia quote a relatively cheap price for egg donation compared to Western countries, Singaporean patients must not forget to factor in the high costs of doing PGS / PGT-A.
A blood sample contains thousands of white blood cells, from which an abundant amount of DNA genetic material can be extracted. By contrast, only a few cells and tiny amount of DNA are extracted from the embryo during PGS (biopsy procedure). This makes it technically simpler and much cheaper to do genetic screening of the Egg Donor's blood sample, as compared to genetic screening of embryos with PGS / PGT-A.
Practice guidelines of the American Society for Reproductive Medicine (www.asrm.org), American College of Medical Genetics and Genomics (www.ACMG.net), and American College of Obstetricians & Gynecologists (www.ACOG.org) recommend screening prospective Egg Donors (blood sample) for common genetic defects such as Cystic Fibrosis, Spinal Muscular Atrophy, Sickle Cell Disease, Alpha and Beta Thalassemia, and Tay-Sachs Disease. In some egg donor agencies or IVF clinics based in Western countries, egg donors may have had their chromosomes tested via high resolution karyotype, and screened for close to 300 genetic disorders.
Please see the high rigorous standards for genetic screening of Egg Donors (blood sample) in Western countries, by clicking on the following links:
Expert opinion by American fertility specialists that highly-expensive PGS (PGT-A) is not necessary for egg donation:
Unfortunately, such rigorous high standards are often not followed by IVF clinics in Malaysia. Instead of genetic testing of the donor's blood sample, patients are strongly encouraged and pushed to opt for more expensive PGS or PGT-A to check for potential genetic defects in embryos. This constitutes an "extra hidden costs" element for overseas egg donation in Malaysia. So when IVF clinics in Malaysia quote a relatively cheap price for egg donation compared to Western countries, Singaporean patients must not forget to factor in the high costs of doing PGS / PGT-A.
A blood sample contains thousands of white blood cells, from which an abundant amount of DNA genetic material can be extracted. By contrast, only a few cells and tiny amount of DNA are extracted from the embryo during PGS (biopsy procedure). This makes it technically simpler and much cheaper to do genetic screening of the Egg Donor's blood sample, as compared to genetic screening of embryos with PGS / PGT-A.
Practice guidelines of the American Society for Reproductive Medicine (www.asrm.org), American College of Medical Genetics and Genomics (www.ACMG.net), and American College of Obstetricians & Gynecologists (www.ACOG.org) recommend screening prospective Egg Donors (blood sample) for common genetic defects such as Cystic Fibrosis, Spinal Muscular Atrophy, Sickle Cell Disease, Alpha and Beta Thalassemia, and Tay-Sachs Disease. In some egg donor agencies or IVF clinics based in Western countries, egg donors may have had their chromosomes tested via high resolution karyotype, and screened for close to 300 genetic disorders.
Please see the high rigorous standards for genetic screening of Egg Donors (blood sample) in Western countries, by clicking on the following links:
A Look at Egg Donor Genetic Testing at EDCB
Learn how egg donor genetic testing at our frozen egg bank network helps hopeful parents receive high-quality donor eggs.
eggdonorcryobank.com
Genetic Test for Egg and Sperm Donors
If you're considering egg or sperm donation, what genetic tests should you request before making your decision?
creatingafamily.org
Egg Donors | ASRM-compliant Oocyte Donation Programme | ManorIVF
ManorIVF has access to an extensive database of egg donors aged 23-32, so there is no waiting time! Contact us now to schedule your initial consultation!
manorivf.com
MyEggBank Donors | Egg Donor Screening & Testing
Choosing your egg donor is one of the biggest decisions you will ever make. Get peace of mind, knowing we have screened and tested all of our donors rigorously.
www.myeggbank.com
Expert opinion by American fertility specialists that highly-expensive PGS (PGT-A) is not necessary for egg donation:
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