新加坡不是中国单身女性冷冻卵子最有利的目的地

Angelica Cheng

Active Member
新加坡不是中国单身女性冷冻卵子最有利的目的地

从 2023 年 7 月起,新加坡允许单身女性的选择性卵子冷冻,这种特殊的医疗程序或许可以吸引许多来自中国大陆的患者。这是因为中国大陆目前禁止单身女性冷冻卵子,然而全国越来越多的受过高等教育的单身女性为了追求职业发展和生活方式追求而推迟结婚和生育。飞涨的房地产价格,加上许多中国大陆大城市的生活、儿童保育和教育费用的上涨,将使年轻夫妇在组建家庭之前必须积累大量储蓄,因此许多职业妇女也必须推迟生育。因此,为她们提供通过海外卵子冷冻保持生育能力的途径将代表有利可图的商机。然而,高昂的成本和严格的卵子冷冻监管可能会阻碍新加坡进入中国医疗旅游市场。

首先,新加坡冷冻卵子的医疗费用比泰国或马来西亚等其他目的地贵得多,这些国家也有许多优秀的生育诊所。通常,卵子冷冻处理周期的费用约为 10000 至 12000新加坡元,约为 5万 至 6万 人民币。除了较高的医疗费用外,日常生活费用和酒店住宿费用也比泰国或马来西亚等便宜的目的地高得多。这是一个重要的成本因素,因为卵子冷冻过程需要几周才能完成。

其次,卵子冷冻仅限于三十七岁以下的女性。因此,这将取消许多高龄的中国单身女性的资格,她们更有可能拥有必要的财务资源来资助手术,因为她们比年轻女性有更多的累积储蓄。

第三,在新加坡,只有已婚妇女才能用冷冻卵子进行试管婴儿手术。这意味着在新加坡冷冻卵子但仍无法找到合适丈夫的外国患者将被永久禁止使用冷冻卵子来怀孕自己的孩子。然后,她们将不得不丢弃或捐赠卵子,或者将卵子出口到更自由的司法管辖区,如澳大利亚或美国,在那里她们可以用捐赠的精子追求单身母亲的身份。然而,将冷冻卵子从一个医疗机构出口到另一个医疗机构存在风险。人类卵子非常脆弱,因此解冻过程必须与冷冻程序相匹配并兼容,否则可能会对卵子造成无法弥补的损害。为了确保最佳结果,最好只有一个试管婴儿实验室同时执行冷冻和解冻程序,并且建议患者避免将冷冻卵子从一个医疗机构转移到另一个医疗机构,这可能没有匹配和兼容的冷冻和解冻方案。此外,由于不可预见的延误、事故和设备故障,冷冻卵子在运输过程中可能会受到不可逆转的损坏。

最后,用PGT-A(植入前基因检测 - 非整倍体)对IVF胚胎进行常规基因检测仍未被批准为新加坡的临床治疗。这是因为新加坡卫生部非常了解几项备受瞩目的临床试验的结果,这些试验最终证明PGT-A不会提高试管婴儿的成功率,并且它是一种侵入性手术,在提取细胞进行基因检测(活检)时可能会损坏胚胎。此外,新加坡PGT-A的本地临床试验显示出不确定的结果,失访率高达72%。然而,受过高等教育的中国单身女性很清楚并极其担心高龄母亲出现遗传缺陷的风险更高,例如唐氏综合症,唐氏综合症在中国大陆受到严重污名化和蔑视。他们当然希望用PGT-A测试他们的试管婴儿胚胎,以避免这种遗传异常,这在返回新加坡使用冷冻卵子时是不可能的。在中国大陆患者的心态中,PGT-A是否对提高他们的试管婴儿成功率没有影响并不重要,是否存在损害胚胎的风险也不重要。简而言之,由于中国大陆内部的社会文化因素,他们痴迷于避免唐氏综合症和其他遗传缺陷。由于抚养和教育的高成本,绝大多数中国女性计划只生一个孩子。因此,这将激励他们在单个后代上进行更多的投资,包括用PGT-A对体外受精胚胎进行昂贵的基因检测。

也许,她们认为在昂贵的基因检测上多花一点钱来确保一个正常健康的孩子会更明智,而不是接受堕胎或浪费更多的钱在唐氏综合症儿童的医疗保健和特殊教育上,这最终会成为社会的负担,让她们自己和家人感到尴尬。鉴于中国患者的心态,更自由司法管辖区的试管婴儿诊所可以利用她们对遗传缺陷的担忧,积极宣传PGT-A检测在当地可用,而在新加坡不可用,导致许多外国中国患者流失到其他国家。

因此,尽管中国大陆患者对海外卵子冷冻的需求肯定很高,但新加坡对社交卵子冷冻的严格监管以及高昂的医疗费用和生活费用, 可能会使其对中国医疗游客的吸引力降低。
 

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Singapore is not the most favorable destination for single Chinese women to freeze their eggs

From July 2023, Singapore will allow elective egg freezing for single women, a special medical procedure that may attract many patients from mainland China. This is because mainland China currently prohibits single women from freezing their eggs, yet an increasing number of highly educated single women across the country are delaying marriage and childbearing in pursuit of career advancement and lifestyle pursuits. Soaring property prices, coupled with rising living, childcare and education costs in many large mainland Chinese cities, will necessitate young couples to accumulate significant savings before starting a family, so many working women will also have to delay childbearing. Therefore, offering them a way to preserve their fertility through overseas egg freezing would represent a lucrative business opportunity. However, high costs and strict egg freezing regulations may hinder Singapore's entry into the Chinese medical tourism market.

Firstly, the medical costs for egg freezing in Singapore are much more expensive than in other destinations such as Thailand or Malaysia, which also have many excellent fertility clinics. Typically, an egg freezing treatment cycle costs about 10,000 to 12,000 Singapore dollars, which is about 50,000 to 60,000 RMB. In addition to higher medical costs, daily living expenses and hotel accommodation are also much higher than in cheaper destinations such as Thailand or Malaysia. This is a significant cost factor because the egg freezing process takes several weeks to complete.

Second, egg freezing is limited to women under the age of thirty-seven. This would therefore disqualify many older single Chinese women who are more likely to have the necessary financial resources to finance the procedure because they have more accumulated savings than younger women.

Third, in Singapore, only married women can undergo IVF procedures with frozen eggs. This means that foreign patients who freeze their eggs in Singapore but still cannot find a suitable husband will be permanently barred from using frozen eggs to conceive their own children. They will then have to discard or donate their eggs, or export them to more liberal jurisdictions such as Australia or the United States, where they can pursue single motherhood with donated sperm. However, there are risks in exporting frozen eggs from one medical institution to another. Human eggs are very fragile, so the thawing process must match and be compatible with the freezing procedure, otherwise it may cause irreparable damage to the eggs. To ensure the best results, it is best to have only one IVF laboratory perform both freezing and thawing procedures, and patients are advised to avoid transferring frozen eggs from one medical institution to another, which may not have matching and compatible freezing and thawing protocols. In addition, frozen eggs may be irreversibly damaged during transportation due to unforeseen delays, accidents and equipment failures.

Finally, routine genetic testing of IVF embryos with PGT-A (preimplantation genetic testing-aneuploidy) is still not approved as a clinical procedure in Singapore. This is because the Singapore Ministry of Health is well aware of the results of several high-profile clinical trials that conclusively proved that PGT-A does not improve IVF success rates and that it is an invasive procedure that can damage embryos when extracting cells for genetic testing (biopsy). In addition, local clinical trials of PGT-A in Singapore have shown inconclusive results with a high loss to follow-up rate of 72%. However, highly educated single Chinese women are well aware and extremely concerned about the higher risk of genetic defects in older mothers, such as Down syndrome, which is highly stigmatized and scorned in mainland China. They certainly want to test their IVF embryos with PGT-A to avoid such genetic abnormalities, which is impossible when returning to Singapore to use frozen eggs. In the mindset of mainland Chinese patients, it does not matter whether PGT-A has no effect on improving their IVF success rates, nor does it matter whether there is a risk of damaging the embryos. In short, due to socio-cultural factors within mainland China, they are obsessed with avoiding Down syndrome and other genetic defects. The vast majority of Chinese women plan to have only one child due to the high costs of raising and educating it, so this will incentivize them to invest more in a single offspring, including expensive genetic testing of IVF embryos using PGT-A.

Perhaps, they think it would be wiser to spend a little more money on expensive genetic testing to ensure a normal and healthy child, rather than undergoing abortion or wasting more money on health care and special education for a child with Down syndrome, which would eventually become a burden on society and an embarrassment to themselves and their families. Given the mentality of Chinese patients, IVF clinics in more liberal jurisdictions can take advantage of their concerns about genetic defects and actively promote the PGT-A test as available locally but not in Singapore, resulting in the loss of many foreign Chinese patients to other countries.

Therefore, while the demand for overseas egg freezing among mainland Chinese patients is certainly high, Singapore’s strict regulations on social egg freezing and high medical and living costs may make it less attractive to Chinese medical tourists.
 

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