Urticaria pigmentosa

[pbcjohn]

https://en.wikipedia.org/wiki/Urticaria_pigmentosa

Any parents also encountered such condition with their babies?

 

[pbcjohn]

Cause by Mastocytosis

https://en.wikipedia.org/wiki/Mastocytosis

Would like to find out or share what usually triggers the an allergic reaction that leads to hives localized to the area of irritation, sometimes referred to as Darier's sign.

 

[pbcjohn]

What is Urticaria (Hives) ?


Urticaria or hives as it is commonly called, is an itchy rash consisting of localized swellings of the skin that usually

last for a few hours before fading away. When urticaria develops around loose tissues of the eyes or lips, the

affected area may swell excessively. Although frightening in appearance, the swelling (called angio-oedema) goes

away in 12 to 24 hours with treatment.

How is urticaria produced ?

Urticaria results from some changes in the small blood vessels of the skin. Such changes are brought about by the

release of some substances in the body, the commonest of which is histamine. Histamine is released from cells

called mast cells by either an allergic or non-allergic reaction.

What causes single attacks of urticaria ?

Acute urticaria, which can last from a few hours to as long as a week is usually caused by drugs, specific foods or a

viral infection. Sometimes, no cause can be detected.

What are the foods that can cause acute and repeated attacks of urticaria ?

Foods that can cause urticaria include :

• Nuts

• Eggs

• Fresh fruits (especially citrus)

• Chocolates

• Fish and shellfish

• Tomatoes

• Milk and cheese

• Spices

• Yeasts

Foods additives and preservatives such as tartrazine (yellow dye) may also be responsible. Hives may appear within

minutes or several hours after ingestion of the food depending on its rate of absorption.

What are the drugs that can cause urticaria ?

Drugs that commonly cause urticaria include :

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• Pain killers/Anti-rheumatics e.g aspirin, codeine

• Antibiotics e.g penicillins, sulphonamides

However, any drug should be suspected even if it has been taken for a long time without ill effects previously. Drugs

commonly cause acute urticaria but they may also aggravate chronic urticaria.

What else can cause urticaria ?

Recurring attacks of urticaria may be caused by physical agents such as; sunlight, cold, pressure and sweat.

Urticaria caused by such agents is called physical urticaria. The causative agent is usually recognized by the patient.

Chronic Urticaria

This is urticaria occurring almost daily and lasting more than two months. In the majority of patients, no cause or

significant aggravating factors can be found. Physical urticaria may be present as well in some patients. Food allergy

is seldom a cause of chronic persistent urticaria even though some foods may aggravate it. Infections such as

candidiasis (a kind of yeast infection) may be a cause, although, not common.

Emotional stress is known to aggravate chronic urticaria in some. Fifty per cent of cases of chronic urticaria, clear

spontaneously in about 6 months.

How is urticaria treated ?

The best treatment for urticaria is to identify and avoid the cause and any aggravating factors. While investigating the

cause, anti-histamines are prescribed for symptomatic relief. Antihistamines, when taken orally, take about 90

minutes to relieve an already formed hive. They work best if taken on a regular basic to prevent the formation of

hives. To avoid side-effects like drowsiness, non-sedative antihistamines are available. Antihistamine creams are

ineffective.

Elimination diets are not helpful unless a particular food is suspected. Skin tests are generally of no use. Blood and

urine test are sometimes carried out to exclude infection as a cause of chronic urticaria.

DEDICATED TO EXCELLENCE IN DERMATOLOGY

By National Skin Centre (Singapore)

Copyright (C) 1995 - National Skin Centre (Singapore)

Last updated

 

[pbcjohn]

my kid currently experience this.
any parents have experience to cure their kids?
please share your experience

From the specialist at kkh, it is not curable. Only thing is to hope that it will go away when your kid is older. They could take some zrytec or telfast to prevent the outbreak. But better to consult the specialist first.

Did the specialist did blood test for your kid to check the tryptase serum analysis?

 

[pbcjohn]

my girl who is almost two encounter this outbreak suddenly few weeks ago.
went to gp one, pd twice but still no use.
all give zrytec and other med.
once she stop taking zrytec, the hives will appear.
have not done any blood test yet.
does it mean she must take zrytec continuously until she grow up?
how old is your child when encounter this?

My baby girl started to had those dark brown spots when she was around 2 mths plus. 3rd mth then she had those blisters outbreak.

Doctor suggest that we give her medication daily so that we could prevent her outbreak. But so far not really that effective for her. Every 2 weeks she will start to have those red flushing, itchiness, and blisters outbreak. Even though we give her medication daily.

 

[pbcjohn]

Suggest u should make an appointment with kkh cleft and lips department to consult the dermatologists there.

Initially PD at the thomson thought she were having sensitive skin. But after doing the blood test at kkh, we found out it's something worst. They found mast cells in her organ. But still border line range. So they referred us to the hematologist. Every mth we have to go to KKH to take blood test to make sure that her mast cell level are not too high.

Recently the doctor infd us, that her level suddenly got so high, they have to do bone marrow testing to confirm it's not systemic mastocytosis. Which is not good news. But doctor ensured us that it is very very rare for children to have this condition.

 

[pbcjohn]

how old is yr girl now? how is she doing?
have u tried tcm?

My girl is 10.5 mths now. Just went to do bone marrow test few days ago. Waiting for result. Not sure about tcm whether it works for her condition or not. Dun think tcm are familiar with this type of medical condition.

 

[gering]

Hi

My daughter is 2.5 years now and is an Urticia Pigmentosa.

Just wondering if you had managed to find more solutions to prevent the reoccurance of the hives?